TFMU-ADPr

CAT: 0804-HY-146248Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146248Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TFMU-ADPr is a general substrate for monitoring poly (ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr has excellent reactivity, generality, stability, and usability. TFMU-ADPr is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes[1].
CAS Number
[2412923-11-4]
UNSPSC
12171500
Target
Poly (ADP-ribose) Glycohydrolase (PARG)
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tfmu-adpr.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(OC[C@H]2O[C@@H]([C@@H]([C@@H]2O)O)OC3=CC=C(C(C(F)(F)F)=CC(O4)=O)C4=C3)(O)=O)(O)=O)([H])N5C6=NC=NC(N)=C6N=C5
Molecular Formula
C25H26F3N5O16P2
Molecular Weight
771.44
References & Citations
[1]Drown BS, et al. Monitoring Poly (ADP-ribosyl) glycohydrolase Activity with a Continuous Fluorescent Substrate. Cell Chem Biol. 2018 Dec 20;25 (12) :1562-1570.e19.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-134354PNP-ADPr
HY-1342618-Br-ADPR
HY-1377042′-Deoxy-ADPR
HY-134354A-01PNP-ADPr (disodium)
HY-1342688-Br-7-CH-ADPR
HY-143484844-TFM
HY-129079-01TFMB- (R) -2-HG
HY-129079A-01TFMB- (S) -2-HG
HY-103246-01TFM-4AS-1
HY-124296-012C-TFM (hydrochloride)

Alternative Products

CatalogName
T74510-01TFMU-ADPr
T74511-01TFMU-ADPr triethylamine
GW4440-1gTFMU
BLG-H042-025His-ADPR / Histidine-ADPR
BLG-E013-50ε-ADPR
T210725-01His-ADPR
BLG-A184-01ADPR-pNP
MBS5801218pNP-ADPr
T78401-01PNP-ADPr disodium
T88805-018-Br-ADPR

Popular Products