TFMB-(R)-2-HG

• UNSPSC Description:

  TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tfmb-r-2-hg.html

• Purity:

  99.91

• Solubility:

  DMSO : 233.33 mg/mL (ultrasonic)

• Smiles:

  O=C([C@@H](CC1)OC1=O)OCC2=CC=CC(C(F)(F)F)=C2

• Molecular Weight:

  288.221

• References & Citations:

  [1]Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1445700-01-5