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2′-Deoxy-ADPR

CAT: 0804-HY-137704Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137704Size:1 Each
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Description
2′-Deoxy-ADPR is an agonist for transient receptor potential melastatin 2 channel (TRPM2 channel) . 2′-Deoxy-ADPR may acts as the signaling molecule in Jurkat T-lymphocytes[1].
CAS Number
111864-49-4
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-deoxy-adpr.html
Smiles
O[C@H]1C[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1COP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)C(O)O4)(O)=O)(O)=O
Molecular Formula
C15H23N5O13P2
Molecular Weight
543.32
References & Citations
[1]Fliegert R, et al., 2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist. Nat Chem Biol. 2017 Sep;13 (9) :1036-1044.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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BLG-D227-052′-deoxy-ADPR
BLG-D228-052′-F-deoxy-ADPR
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BLG-E013-50ε-ADPR
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D 228-012'- Deoxy- 2'- fluoroadenosine- 5'- O- diphosphoribose (2'-F-dADPR / 2'-F-deoxy-ADPR), sodium salt
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