2′-Deoxy-ADPR

• Description:

  2′-Deoxy-ADPR is an agonist for transient receptor potential melastatin 2 channel (TRPM2 channel) . 2′-Deoxy-ADPR may acts as the signaling molecule in Jurkat T-lymphocytes[1].

• UNSPSC:

  12352005

• Target:

  TRP Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-adpr.html

• Smiles:

  O[C@H]1C[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1COP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)C(O)O4)(O)=O)(O)=O

• Molecular Formula:

  C15H23N5O13P2

• Molecular Weight:

  543.32

• References & Citations:

  [1]Fliegert R, et al., 2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist. Nat Chem Biol. 2017 Sep;13 (9) :1036-1044.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  111864-49-4