PARP-1/HDAC-IN-1
CAT:
804-HY-146160
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PARP-1/HDAC-IN-1
- CAS Number: 3032621-10-3
- UNSPSC Description: PARP-1/HDAC-IN-1 is a PARP-1/HDAC6 dual targeting inhibitor with IC50s of 68.90 nM and 510 nM, respectively. PARP-1/HDAC-IN-1 displays remarkable anticancer, anti-migration and anti-angiogenesis activities[1].
- Target Antigen: HDAC; PARP
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/parp-1-hdac-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: NC(C1=CC=CC2=CN(N=C21)C3=CC=C(C=C3)OCC4=CC=C(C=C4)C(NO)=O)=O
- Molecular Weight: 402.40
- References & Citations: [1]Ziwei Chi, et al. Design, synthesis and antitumor activity study of PARP-1/HDAC dual targeting inhibitors. Bioorg Med Chem Lett. 2022 Sep 1;71:128821.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported