PARP-1/HDAC-IN-1

PARP-1/HDAC-IN-1

• CAS Number: 3032621-10-3
• UNSPSC Description: PARP-1/HDAC-IN-1 is a PARP-1/HDAC6 dual targeting inhibitor with IC50s of 68.90 nM and 510 nM, respectively. PARP-1/HDAC-IN-1 displays remarkable anticancer, anti-migration and anti-angiogenesis activities[1].
• Target Antigen: HDAC; PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/parp-1-hdac-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: NC(C1=CC=CC2=CN(N=C21)C3=CC=C(C=C3)OCC4=CC=C(C=C4)C(NO)=O)=O
• Molecular Weight: 402.40
• References & Citations: [1]Ziwei Chi, et al. Design, synthesis and antitumor activity study of PARP-1/HDAC dual targeting inhibitors. Bioorg Med Chem Lett. 2022 Sep 1;71:128821.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported