Tau-aggregation-IN-4

• Description:

  Tau-aggregation-IN-4 is a Tau-aggregation inhibitor (EC50 = 2.99 μM) . Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases[1].

• UNSPSC:

  12352005

• Target:

  Tau Protein

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  O=C(C1=CNC2=C1C=CC(NC(CCC3(CCC#C)N=N3)=O)=C2)NC4=CC=CC=C4

• Molecular Formula:

  C23H21N5O2

• Molecular Weight:

  399.45

• References & Citations:

  [1]Conway LP, et al. Discovery of a tau-aggregate clearing compound that covalently targets P4HB. Cell Chem Biol. 2025 Oct 16;32 (10) :1235-1248.e34.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported