AEP-IN-1

• Description :

  AEP-IN-1 (Compound 13e) is a CNS agent-like non-covalent inhibitor of asparagine endopeptidase (AEP), with the IC50 of 89 nM. AEP-IN-1 can be used for the research of numerous neurological diseases such as Alzheimer’s disease (AD) [1].

• UNSPSC :

  12352005

• Target :

  Cathepsin

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/aep-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1CCN(C2=CC(N3CCOCC3)=CC=C2N)CC1)OCC

• Molecular Formula :

  C18H27N3O3

• Molecular Weight :

  333.43

• References & Citations :

  [1]Lorenzo Calugi, et al. Modular synthesis of 2,4-diaminoanilines as CNS drug-like non-covalent inhibitors of asparagine endopeptidase. Bioorg Med Chem. 2022 Jun 1;63:116746.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3032742-75-6]