AEP-IN-3

• Target:

  Others|||Cysteine Protease

• Related Pathways:

  Proteases/Proteasome|||Others

• Bioactivity:

  AEP-IN-3 (compound 18) is an orally administered, potent asparagine endopeptidase (AEP) inhibitor that effectively crosses the blood-brain barrier. It boasts an IC50 of 7.8 ± 0.9 nM and is applicable in Alzheimer's Disease (AD) research [1].

• Smiles:

  C(=O)(C1(CC1)C2=CC=C(OC(F)(F)F)C=C2)N3[C@H](C(N[C@@H](CC(N)=O)C#C)=O)C[C@@H](F)C3

• Molecular Formula:

  C21H21F4N3O4

• Molecular Weight:

  455.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2978521-26-3