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AEP-IN-3

CAT: 0931-T85598-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T85598-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2978521-26-3
Target
Others, Cysteine Protease
Related Pathways
Proteases/Proteasome, Others
Bioactivity
AEP-IN-3 (compound 18) is an orally administered, potent asparagine endopeptidase (AEP) inhibitor that effectively crosses the blood-brain barrier. It boasts an IC50 of 7.8 ± 0.9 nM and is applicable in Alzheimer's Disease (AD) research [1].
Smiles
C(=O)(C1(CC1)C2=CC=C(OC(F)(F)F)C=C2)N3[C@H](C(N[C@@H](CC(N)=O)C#C)=O)C[C@@H](F)C3
Molecular Formula
C21H21F4N3O4
Molecular Weight
455.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C