NF-κB-IN-1

CAT: 0931-T9105-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T9105-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1227098-15-8

Target

IκB/IKK, NF-κB

Related Pathways

NF-κB

Purity

0.9929

Bioactivity

NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis (3,4-dimethoxyphenyl) -4-[ (4-hydroxy-3-methoxyphenyl) methylene]-, (1E,6E) -) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.

Smiles

COc1ccc(\C=C\C(=O)C(=Cc2ccc(O)c(OC)c2)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC

Molecular Formula

C31H30O8

Molecular Weight

530.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
BA8604-1	NF-κB-IN-1
BUP07719-01	NF-?B-IN-1
GTR19185557-01	NF-κB/PON1-IN-1
HY-175227	STAT3/NF-κB-IN-1
HY-174138-01	NF-κB degrader 1
BUP05080-01	NF-?B/MAPK-IN-1
GTR19185546-01	NF-κB/MAPK-IN-1
HY-168710-01	TLR4/NF-κB-IN-1
HY-173488	NF-κB/HIF-1α-IN-1
HY-149496	Akt/NF-κB/MAPK-IN-1

NF-κB-IN-1

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