NF-?B-IN-1

• Target :

  I?B/IKK|||NF-?B

• Related Pathways :

  NF-?B

• Purity :

  0.9929

• Bioactivity :

  NF-?B-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis (3,4-dimethoxyphenyl) -4-[ (4-hydroxy-3-methoxyphenyl) methylene]-, (1E,6E) -) is a potent NF-?B signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-?B-IN-1 directly inhibits IKK to block NF-?B activation. NF-?B-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.

• Smiles :

  COc1ccc(\C=C\C(=O)C(=Cc2ccc(O)c(OC)c2)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC

• Molecular Formula :

  C31H30O8

• Molecular Weight :

  530.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1227098-15-8