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NLRP3-IN-7

CAT: 0804-HY-145911Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145911Size:1 Each
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Description
NLRP3-IN-7 (Compound 36) is a selective NLRP3 inflammasome inhibitor. NLRP3-IN-7 effectively blocks the assembly of the NLRP3 inflammasome[1].
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-7.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(OC)C=C1CN2C(/C(SC2=S)=C/C3=CC=C(C=C3)S(N)(=O)=O)=O
Molecular Formula
C18H15ClN2O4S3
Molecular Weight
454.97
References & Citations
[1]Zuo D, et al. Design and synthesis of an N-benzyl 5- (4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor. Bioorg Med Chem Lett. 2022 Jun 1;65:128693.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3

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