NLRP3-IN-7

NLRP3-IN-7

• UNSPSC Description: NLRP3-IN-7 (Compound 36) is a selective NLRP3 inflammasome inhibitor. NLRP3-IN-7 effectively blocks the assembly of the NLRP3 inflammasome[1].
• Target Antigen: NOD-like Receptor (NLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/nlrp3-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=CC=C(OC)C=C1CN2C(/C(SC2=S)=C/C3=CC=C(C=C3)S(N)(=O)=O)=O
• Molecular Weight: 454.97
• References & Citations: [1]Zuo D, et al. Design and synthesis of an N-benzyl 5-(4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor. Bioorg Med Chem Lett. 2022 Jun 1;65:128693.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported