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NLRP3-IN-24

CAT: 0804-HY-157147Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157147Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3-IN-24 (Compounds 15a) is an inhibitor against NLRP3. NLRP3-IN-24 has an inhibitory effect on the activation of NLRP3 inflammasome[1].
UNSPSC
12352211
Target
Interleukin Related; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-24.html
Solubility
10 mM in DMSO
Smiles
O=C(C=C1[Si](C)(C)C)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
Molecular Formula
C19H26O3Si
Molecular Weight
330.49
References & Citations
[1]Shete S S, et al. Sila-CBD Derivatives as Inhibitors of Heme-Induced NLRP3 Inflammasome: Application in Hemolytic Diseases[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-1; IL-6

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