BI-10

• Description:

  BI-10 is an antifungal compound. BI-10 combined with Fluconazole can inhibit hyphal growth, result in ROS accumulation, and decrease mitochondrial membrane potential (MMP) as well as altering membrane permeability[1].

• UNSPSC:

  12352005

• Target:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/bi-10.html

• Solubility:

  10 mM in DMSO

• Smiles:

  BrC1=CC=CC(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)=C1O

• Molecular Formula:

  C23H17BrN2O

• Molecular Weight:

  417.30

• References & Citations:

  [1]Jiang Y, et al. Synthesis and antifungal evaluation of phenol-derived bis (indolyl) methanes combined with FLC against Candida albicans. Bioorg Med Chem Lett. 2022;58:128525.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2759037-58-4]