eIF4A3-IN-4

• UNSPSC Description:

  eIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.

• Target Antigen:

  Eukaryotic Initiation Factor (eIF)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/eif4a3-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C1=C2C(C=CC([N+]([O-])=O)=C2)=NC(C3=CC=C(C4=CC=C(CCCC)C=C4)O3)=C1)=O

• Molecular Weight:

  416.43

• References & Citations:

  [1]Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64(21):15727-15746.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2861994-92-3