eIF4A3-IN-4

eIF4A3-IN-4

• CAS Number: 2861994-92-3
• UNSPSC Description: eIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.
• Target Antigen: Eukaryotic Initiation Factor (eIF)
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/eif4a3-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: OC(C1=C2C(C=CC([N+]([O-])=O)=C2)=NC(C3=CC=C(C4=CC=C(CCCC)C=C4)O3)=C1)=O
• Molecular Weight: 416.43
• References & Citations: [1]Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64(21):15727-15746.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported