EIF4A3-IN-4

• Description :

  EIF4A3-IN-4 is a novel eIF4A inhibitor with an IC50 value of 8.6 μM.

• UNSPSC :

  12352005

• Target :

  Eukaryotic Initiation Factor (eIF)

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/eif4a3-in-4.html

• Purity :

  99.8

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C1=C2C(C=CC([N+]([O-])=O)=C2)=NC(C3=CC=C(C4=CC=C(CCCC)C=C4)O3)=C1)=O

• Molecular Formula :

  C24H20N2O5

• Molecular Weight :

  416.43

• References & Citations :

  [1]Zerio CJ, et al. Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action. J Med Chem. 2021 Nov 11;64 (21) :15727-15746.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EIF4

• CAS Number :

  [2861994-92-3]