HPK1-IN-11

HPK1-IN-11

• CAS Number: 2734167-68-9
• UNSPSC Description: HPK1-IN-11 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-11 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 2)[1].
• Target Antigen: MAP4K
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hpk1-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: N#CC1=CC2=C(C=C1C3=C(OC)C=CC=C3)C(C4=CC(OCC5N6CCN(C5)C)=C6C=C4)=NN2
• Molecular Weight: 451.52
• References & Citations: [1]Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported