HPK1-IN-9

HPK1-IN-9

• CAS Number: 2734168-78-4
• UNSPSC Description: HPK1-IN-9 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-9 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 112) [1].
• Target Antigen: MAP4K
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hpk1-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1CC(C1)N(C)C)C2=CC=C(C3=CNC4=C3N=C(C5=CC=C6C(OCC7N6CCN(C7)C)=C5)C=N4)C=C2
• Molecular Weight: 523.63
• References & Citations: [1]Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported