(S) -HH2853

CAT: 0804-HY-144881-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-144881-01Size:1 mg
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Description
(S) -HH2853 (compound 200), a PYRIDINO five membered aromatic ring compound, is a potent EZH1/2 dual inhibitor with an IC50 of [1].
CAS Number
[2202678-05-3]
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-hh2853.html
Solubility
10 mM in DMSO
Smiles
C[C@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24
Molecular Formula
C31H36F3N7O3
Molecular Weight
611.66
References & Citations
[1]Xuxing Chen, et al. PYRIDINO five membered aromatic ring compounds, preparation method and application thereof. WO2018045971A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EZH1; EZH2

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