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(R) -HH2853

CAT: 0804-HY-144882-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-144882-01Size:5 mg
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Description
(R) -HH2853 is a mutant EZH2 inhibitor with an IC50 of EZH2-Y641F. (R) -HH2853 can be used for cancer and autoimmune diseases (WO2018045971A1; compound 201) [1].
CAS Number
2202678-06-4
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-hh2853.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24
Molecular Formula
C31H36F3N7O3
Molecular Weight
611.66
References & Citations
[1]Xuxing Chen, et al. Pyrido five-element aromatic ring compound, preparation method therefor and use thereof. WO2018045971A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EZH2

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