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(S, S) -D211

CAT: 0804-HY-122715Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-122715Size:1 Each
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Description
(S, S) -D211 is a stereoisomer of D211. (S, S) -D211 belongs to PBD dimer family with DNA damage activity. (S, S) -D211 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number
[1971075-99-6]
UNSPSC
12352005
Target
ADC Payload; DNA/RNA Synthesis
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1N2[C@@](C=NC3=CC(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(CC7=CC=CC=C7C6)C5=O)=C4)OC)=C(OC)C=C31)([H])CC8=CC=CC=C8C2
Molecular Formula
C39H36N4O6
Molecular Weight
656.73
References & Citations
[1]Smith SW, et al. Design and Synthesis of Isoquinolidinobenzodiazepine Dimers, a Novel Class of Antibody-Drug Conjugate Payload. ACS Med Chem Lett. 2017 Dec 6;9 (1) :56-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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M13086-01D211
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T29263-01(S, S) -D211

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