AChE/BChE-IN-2

• UNSPSC Description:

  AChE/BChE-IN-2 (Compound 13b) is a potent inhibitor of AChE/BChE (AChE IC50 = 0.96 ± 0.14 µM, BChE IC50 = 1.23 ± 0.23 µM). AChE/BChE-IN-2 has the potential for the research of AD diseases[1].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ache-bche-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCC(NCCC1=CNC2=C1C=C(OC)C=C2)=O)/C=C/C3=CC=C(O)C(OC)=C3

• Molecular Weight:

  423.46

• References & Citations:

  [1]Singh YP, et al. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease. Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2761991-42-6