AChE/BChE-IN-2

AChE/BChE-IN-2

• CAS Number: 2761991-42-6
• UNSPSC Description: AChE/BChE-IN-2 (Compound 13b) is a potent inhibitor of AChE/BChE (AChE IC50 = 0.96 ± 0.14 µM, BChE IC50 = 1.23 ± 0.23 µM). AChE/BChE-IN-2 has the potential for the research of AD diseases[1].
• Target Antigen: Cholinesterase (ChE)
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/ache-bche-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCC(NCCC1=CNC2=C1C=C(OC)C=C2)=O)/C=C/C3=CC=C(O)C(OC)=C3
• Molecular Weight: 423.46
• References & Citations: [1]Singh YP, et al. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease. Bioorg Med Chem. 2021 Sep 15;46:116385. doi: 10.1016/j.bmc.2021.116385.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported