NS2B/NS3-IN-6

NS2B/NS3-IN-6

• CAS Number: 2459657-57-7
• UNSPSC Description: NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively[1].
• Target Antigen: Virus Protease
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/ns2b-ns3-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(N1[C@@H](CCC1)C(NC2=NC3=CC(O)=C(O)C=C3S2)=O)(C4=CC=C(C=C4)C)=O
• Molecular Weight: 433.50
• References & Citations: [1]Maus H, et al. SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases. Bioorg Med Chem. 2021 Oct 1;47:116392.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported