NS2B/NS3-IN-7

NS2B/NS3-IN-7

• CAS Number: 3035421-16-7
• UNSPSC Description: NS2B/NS3-IN-7 (compound 26) is a highly potent Zika virus NS2B-NS3 protease inhibitor with a Ki value of 2.33 nM. NS2B/NS3-IN-7 can reduce amounts of ZIKV-infected cells[1].
• Target Antigen: Flavivirus; Virus Protease
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/ns2b-ns3-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: NCCCC[C@@H](C(N[C@H]1CCCCN)=O)NC(CC2=CC=CC(CNC([C@@H](CCC3CCCCC3)NC([C@@H](CCCCNC1=O)NC(N)=N)=O)=O)=C2)=O
• Molecular Weight: 740.98
• References & Citations: [1]Huber S, et al. Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J Med Chem. 2022 May 12;65(9):6555-6572.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported