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NS2B/NS3-IN-4

CAT: 0804-HY-144736Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144736Size:1 Each
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Description
NS2B/NS3-IN-4 (Compound 34e) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.69 µM and 1.04 µM against DENV2 and ZIKV NS2B/NS3 proteases, respectively[1].
CAS Number
2910757-30-9
UNSPSC
12352005
Target
Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ns2b-ns3-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=CC(O)=C(C=C2O1)O)NC3=CC=CC=C3
Molecular Formula
C15H11NO4
Molecular Weight
269.25
References & Citations
[1]Maus H, et al. SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases. Bioorg Med Chem. 2021 Oct 1;47:116392.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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