Axl-IN-3

Axl-IN-3

• CAS Number: 2783991-34-2
• UNSPSC Description: Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases[1].
• Target Antigen: TAM Receptor
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/axl-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(C=C1)N2C=C(C=N2)C3=NNC4=C3C=C(C(Cl)=C4)N[C@@H]5CCN(C5)C6COC6
• Molecular Weight: 464.95
• References & Citations: [1]Pearly Shuyi Ng, et al. Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors. Bioorg Med Chem. 2021 Nov 1;49:116437.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported