Login

Axl-IN-3

CAT:
804-HY-144706
Size:
Inquire
Price:
Ask
For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Axl-IN-3 - image 1

Axl-IN-3

  • CAS Number: 2783991-34-2
  • UNSPSC Description: Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases[1].
  • Target Antigen: TAM Receptor
  • Type: Reference compound
  • Related Pathways: Protein Tyrosine Kinase/RTK
  • Applications: Cancer-Kinase/protease
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/axl-in-3.html
  • Solubility: 10 mM in DMSO
  • Smiles: COC1=CC=C(C=C1)N2C=C(C=N2)C3=NNC4=C3C=C(C(Cl)=C4)N[C@@H]5CCN(C5)C6COC6
  • Molecular Weight: 464.95
  • References & Citations: [1]Pearly Shuyi Ng, et al. Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors. Bioorg Med Chem. 2021 Nov 1;49:116437.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported