Axl-IN-3
CAT:
804-HY-144706
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Axl-IN-3
- CAS Number: 2783991-34-2
- UNSPSC Description: Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases[1].
- Target Antigen: TAM Receptor
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/axl-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC=C(C=C1)N2C=C(C=N2)C3=NNC4=C3C=C(C(Cl)=C4)N[C@@H]5CCN(C5)C6COC6
- Molecular Weight: 464.95
- References & Citations: [1]Pearly Shuyi Ng, et al. Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors. Bioorg Med Chem. 2021 Nov 1;49:116437.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported