CREB-IN-1 (TFA)

CAT: 0804-HY-144318-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-144318-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

CREB-IN-1 TFA is a potent, orally active CREB inhibitor (IC50=0.18 μM) . CREB-IN-1 TFA inhibits breast cancer cell growth[1].

CAS Number

2912285-84-6

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/creb-in-1-tfa.html

Solubility

10 mM in DMSO

Smiles

NCCCOC1=C(C=C2C=CC=CC2=C1)C(NCCOC3=CC4=CC=CC=C4C=C3C(NC5=CC=C(C=C5OP(O)(O)=O)Cl)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C35H32ClF3N3O10P

Molecular Weight

778.06

References & Citations

[1]Peng J, et al. Design, Synthesis and Biological Evaluation of Prodrugs of 666-15 as Inhibitors of CREB-Mediated Gene Transcription. ACS Med Chem Lett. 2022; 13 (3) :388-395.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-P1681A-01	GpTx-1 (TFA)
HY-173076A-01	HDAC11-IN-1 (TFA)
HY-P3139A	TPP-1 (TFA)
HY-P1409A-01	ADWX 1 (TFA)
HY-P2785A-01	Phrixotoxin-1 (TFA)
HY-P5334A-01	AADvac 1 (TFA)
HY-P1985A-01	Notch 1 (TFA)
HY-19617B-01	EGFR-IN-1 (TFA)
HY-122641D-01	Deltasonamide 1 (TFA)
HY-P0269A-01	Magainin 1 (TFA)

Alternative Products

Catalog	Name
T64247-01	CREB-IN-1 TFA
GTR19213125	Aβ-IN-1 TFA
BUP21757	Aß-IN-1 TFA
LWD75992-01	SETD2-IN-1 TFA
T40251	DTAGV-1 TFA
T204739-01	TMPRSS6-IN-1 TFA
TP3667-01	Phlotoxin-1 TFA
T63447	FTO-IN-1 TFA
T76198-01	TPP-1 TFA
T76071-01	Epinecidin-1 TFA

CREB-IN-1 (TFA)

Related Products

Alternative Products

Popular Products