HDAC1-IN-4

HDAC1-IN-4

• CAS Number: 2482998-39-8
• UNSPSC Description: HDAC1-IN-4 (JX34) is a potent Plasmodium falciparum HDAC1 inhibitor shows antimalarial activity (IC50 [1].
• Target Antigen: HDAC; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Cell Cycle/DNA Damage;Epigenetics
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/hdac1-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CN=C(N(CC2)CC32CN(CC4=CN(C)C5=C4C=CC(Br)=C5)C3)N=C1)NO.[H]Cl
• Molecular Weight: 507.81
• References & Citations: [1]Wang M, et al. Drug Repurposing of Quisinostat to Discover Novel Plasmodium falciparum HDAC1 Inhibitors with Enhanced Triple-Stage Antimalarial Activity and Improved Safety. J Med Chem. 2022;65(5):4156-4181.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported