HDAC1-IN-4

CAT: 0804-HY-144298Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144298Size:1 Each
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Description
HDAC1-IN-4 (JX34) is a potent Plasmodium falciparum HDAC1 inhibitor shows antimalarial activity (IC50 [1].
CAS Number
[2482998-39-8]
UNSPSC
12352005
Target
HDAC; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hdac1-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN=C(N(CC2)CC32CN(CC4=CN(C)C5=C4C=CC(Br)=C5)C3)N=C1)NO.[H]Cl
Molecular Formula
C21H24BrClN6O2
Molecular Weight
507.81
References & Citations
[1]Wang M, et al. Drug Repurposing of Quisinostat to Discover Novel Plasmodium falciparum HDAC1 Inhibitors with Enhanced Triple-Stage Antimalarial Activity and Improved Safety. J Med Chem. 2022;65 (5) :4156-4181.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium

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