Metallo-β-lactamase-IN-2

• UNSPSC Description:

  Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.1 μM (VIM-1), 1.3 μM (NDM-1), and 5.0 μM (IMP-7), respectively[1].

• Target Antigen:

  Bacterial; Beta-lactamase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/metallo-β-lactamase-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=C(Cl)C(Cl)=C1)CCS

• Molecular Weight:

  250.14

• References & Citations:

  [1]Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1501705-61-8