Metallo-β-lactamase-IN-7
CAT:
804-HY-143415
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Metallo-β-lactamase-IN-7
- CAS Number: 2752453-58-8
- UNSPSC Description: Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC50s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains[1].
- Target Antigen: Bacterial; Beta-lactamase
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/metallo-β-lactamase-in-7.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=NC=CN1CC2=CC=C3N=C(N)SC3=C2)O
- Molecular Weight: 274.30
- References & Citations: [1]Yan YH, Li W, Chen W, et al. Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-β-lactamase inhibitors. Eur J Med Chem. 2022;228:113965.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported