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NSC 828467

CAT: 0804-HY-144222Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144222Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC 828467 exhibited significant in vitro anticancer activity, and it is one of the top-five CA IX inhibitors with an IC50 value of 27.2nM.
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-828467.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)NC2=NC(N/N=C/C3=NC=CC=C3)=NC(NC4=CC=CC=C4)=N2)=O
Molecular Formula
C21H19N9O2S
Molecular Weight
461.50
References & Citations
[1]Tawfik HO, et al. Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach. Eur J Med Chem. 2022 Feb 12;232:114190.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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