NSC 104999

CAT: 0804-HY-180480Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-180480Size:1 Each

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Description

NSC 104999 is a Grb7 SH2 domain binder with moderate affinity (Kd = 32.3 μM) . NSC 104999 exhibits anticancer activity against breast cancer[1].

CAS Number

1118745-14-4

UNSPSC

12352005

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(C1=CC=C(C(NC2=CC(C3=NCCN3)=CC(C(NCCCC)=O)=C2)=O)C=C1)NC4=CC(C5=NCCN5)=CC(C(NCCCC)=O)=C4

Molecular Formula

C36H42N8O4

Molecular Weight

650.77

References & Citations

[1]Ambaye ND, et al. The discovery of phenylbenzamide derivatives as Grb7-based antitumor agents. ChemMedChem. 2013 Feb;8 (2) :280-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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