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NSC 694621

CAT: 0804-HY-147288-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147288-01Size:5 mg
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Description
NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 μM (PCAF/H31-21) . NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].
CAS Number
104857-29-6
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-694621.html
Purity
98.67
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=CC=CN=C2SN1C3=CC=C(C=C3)OC
Molecular Formula
C13H10N2O2S
Molecular Weight
258.30
References & Citations
[1]Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19 (12) :3678-89.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GCN5/PCAF

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