RET-IN-14

CAT: 0804-HY-144170Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-144170Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of [1]

CAS Number

2755843-62-8

UNSPSC

12352005

Target

Btk; RET

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ret-in-14.html

Solubility

10 mM in DMSO

Smiles

NC1=C(C2=CC=C(C=C2)NC(OC)=O)C3=NC4=C(C(NC[C@@H](OC5=NC=C(F)C=C5CN3)C)=O)C=NN14

Molecular Formula

C24H23FN8O4

Molecular Weight

506.49

References & Citations

[1]Jing Wang, et al. Compounds with macrocyclic structure and their uses. WO2021244609A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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