Metallo-β-lactamase-IN-8
CAT:
804-HY-146165
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Metallo-β-lactamase-IN-8
- CAS Number: 1610537-25-1
- UNSPSC Description: Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].
- Target Antigen: Bacterial; Beta-lactamase
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/metallo-β-lactamase-in-8.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NO)C1=CC=C(NS(=O)(C2=CC=C(Cl)C=C2)=O)C=C1
- Molecular Weight: 326.76
- References & Citations: [1]Li JQ, et, al. Hydroxamic acid with benzenesulfonamide: An effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors. Bioorg Chem. 2020 Dec;105:104436.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported