Cdc7-IN-8

• Description :

  Cdc7-IN-8 is a potent inhibitor of Cdc7. Cdc7 is a serine/threonine kinase which activates MCM promotion by phosphorylating the microchromosome maintenance protein (MCM protein), an important element of the DNA replication initiator. Cdc7-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021032170A1, compound 1-1/1-2) [1].

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdc7-in-8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(C3=C(O2)C4=CNN=C4CCC3)N=C(N1)[C@@H]5CC6CCN5CC6

• Molecular Formula :

  C19H21N5O2

• Molecular Weight :

  351.40

• References & Citations :

  [1]Lun Lu, et al. Tetracyclic compound used as cdc7 inhibitor. Patent WO2021032170A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2606780-38-3]