Cdc7-IN-12

• Description :

  Cdc7-IN-12 (compound 1) is a potent CDC7 inhibitor with an IC50 of 50 of 100-1000 nM in COLO205 cells. Cdc7-IN-12 has the potential for the research of cancer[1].

• CAS Number :

  [2764865-33-8]

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdc7-in-12.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=C2CCCOC3=C(SC(C(N1)=O)=C23)C4=CC=NC=C4

• Molecular Formula :

  C16H14N2O2S

• Molecular Weight :

  298.36

• References & Citations :

  [1]Huang XIanhai, et al. Heterocyclic pericondensed cdc7 kinase inhibitors for the treatment of cancer. WO2022055963A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDC