Cdc7-IN-18

• Target:

  Others|||CDK

• Related Pathways:

  Others|||Cell Cycle/Checkpoint

• Bioactivity:

  Cdc7-IN-18 (compound 1-2) is a highly effective inhibitor of the CDC7 enzyme, with an IC50 value of 1.29 nM for the Cdc7/DBF4 enzyme. Additionally, this compound exhibits strong antiproliferative activities, with an IC50 value of 53.62 nM in COLO205 cells [1].

• Smiles:

  O=C1C2=C(C3=C(S2)C=4C(CCC3)=NNC4)NC(=N1)[C@@H]5N6CCC(C5)CC6

• Molecular Formula:

  C19H21N5OS

• Molecular Weight:

  367.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2562329-14-8