Cdc7-IN-18

• UNSPSC Description:

  Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdc7-in-18.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(NC([C@]3([H])N4CCC(CC4)C3)=N1)C5=C(C6=CNN=C6CCC5)S2

• Molecular Weight:

  367.47

• References & Citations:

  [1]Li Gang, et al. Tetracyclic compounds as cdc7 inhibitors. WO2020239107A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2562329-14-8