Cdc7-IN-18

Cdc7-IN-18

• CAS Number: 2562329-14-8
• UNSPSC Description: Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdc7-in-18.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(NC([C@]3([H])N4CCC(CC4)C3)=N1)C5=C(C6=CNN=C6CCC5)S2
• Molecular Weight: 367.47
• References & Citations: [1]Li Gang, et al. Tetracyclic compounds as cdc7 inhibitors. WO2020239107A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported