Cdc7-IN-21

• UNSPSC Description:

  Cdc7-IN-21 (compound 10c) is a potent and selective Cdc7 inhibitor with an IC50 of 0.07 nM. Cdc7-IN-21 can be used to study cancer[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdc7-in-21.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N=C(CN2CCCC2)NC3=C1SC(C4=CNN=C4C)=C3

• Molecular Weight:

  315.39

• References & Citations:

  [1]Kurasawa O, et al. 2-Aminomethylthieno [3, 2-d] pyrimidin-4 (3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase[J]. Bioorganic & Medicinal Chemistry, 2017, 25(14): 3658-3670.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1330781-04-8