FY-56

CAT: 0804-HY-143238Size: 1 EachDry Ice: NoHazardous: No

CAT#: HY-143238Size: 1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

FY-56 is a highly potent and selective LSD1/KDM1A inhibitor (IC50=42 nM) and exhibits high selectivity over MAO-A/B. FY-56 induces differentiation of MOLM-13 and MV4-11 cell and has the potential for AML research[1].

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fy-56.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2=C(C13NCCC4=CC(O)=C(C=C43)O)C=CC=C2)CC5=C(C=CC=C5)F

Molecular Formula

C23H19FN2O3

Molecular Weight

390.41

References & Citations

[1]Chao Yang, et al. Discovery of natural product-like spirooxindole derivatives as highly potent and selective LSD1/KDM1A inhibitors for AML treatment. Bioorg Chem. 2022 Mar; 120:105596

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KDM1/LSD1

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HY-172791	HDAC6-IN-56
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