FY-56

• UNSPSC Description:

  FY-56 is a highly potent and selective LSD1/KDM1A inhibitor (IC50=42 nM) and exhibits high selectivity over MAO-A/B. FY-56 induces differentiation of MOLM-13 and MV4-11 cell and has the potential for AML research[1].

• Target Antigen:

  Histone Demethylase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fy-56.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C2=C(C13NCCC4=CC(O)=C(C=C43)O)C=CC=C2)CC5=C(C=CC=C5)F

• Molecular Weight:

  390.41

• References & Citations:

  [1]Chao Yang, et al. Discovery of natural product-like spirooxindole derivatives as highly potent and selective LSD1/KDM1A inhibitors for AML treatment. Bioorg Chem. 2022 Mar; 120:105596

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported