FY-21

• Target:

  Histone Demethylase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9988

• Bioactivity:

  FY-21 is a selective LSD1 inhibitor (IC50= 340 nM) that inhibits proliferation and colony formation of leukemia cells, decreases mRNA levels of the transcription factors HOXA9 and MEIS1, and can be used in the study of leukemia.

• Smiles:

  OC1=C(O)C=C(CCNC2C3=CC=C([N+]([O-])=O)C=C3)C2=C1.OC(C(F)(F)F)=O

• Molecular Formula:

  C17H15F3N2O6

• Molecular Weight:

  400.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C