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KCa2 channel modulator 2

CAT:
804-HY-142735
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
KCa2 channel modulator 2 - image 1

KCa2 channel modulator 2

  • CAS Number: 2764618-34-8
  • UNSPSC Description: KCa2 channel modulator 2 (compound 2q) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 2 exhibits similar potency on the rat KCa2.2a and human KCa2.3 channel subtypes, with EC50s of 0.64 μM and 0.60 μM, respectively[1]
  • Target Antigen: Potassium Channel
  • Type: Reference compound
  • Related Pathways: Membrane Transporter/Ion Channel
  • Applications: Neuroscience-Neuromodulation
  • Field of Research: Neurological Disease
  • Assay Protocol: https://www.medchemexpress.com/kca2-channel-modulator-2.html
  • Solubility: 10 mM in DMSO
  • Smiles: CC1=CC(NC2=C(C=CC(Cl)=C2)F)=NC(N3C(C)=CC(C)=N3)=N1
  • Molecular Weight: 331.78
  • References & Citations: [1]El-Sayed NS, et al. Structure-Activity Relationship Study of Subtype-Selective Positive Modulators of KCa2 Channels. J Med Chem. 2022;65(1):303-322.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported