ZL-2201

• Description:

  ZL-2201 is a potent DNA-PK inhibitor with an IC50 of 1 nM (WO2021104277A1, compound 5) [1].

• UNSPSC:

  12352005

• Target:

  DNA-PK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/zl-2201.html

• Purity:

  99.16

• Solubility:

  10 mM in DMSO

• Smiles:

  CS(O)(=O)=O.O=C1N(C)C2=CN=C(NC3=CN4C(C=C3C)=NC=N4)N=C2N1N5CC(O6)CCC6C5

• Molecular Formula:

  C20H25N9O5S

• Molecular Weight:

  503.53

• References & Citations:

  [1]Pyrimidoimidazole compounds used as dna-pk inhibitors. WO2021104277A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2865115-39-3]