ZL-Pin13

CAT: 0804-HY-143903Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-143903Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ZL-Pin13 is a high potent cell-active covalent inhibitor targeting the Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) with an IC50 of 67 nM. ZL-Pin13 effectively inhibits the proliferation and downregulated the Pin1 substrates in MDA-MB-231 cells[1].
CAS Number
[2883498-73-3]
UNSPSC
12352005
Target
PIN1
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zl-pin13.html
Solubility
10 mM in DMSO
Smiles
O=C(CSC12CCN(CC2)C(CCl)=O)N1CC3=CC=C(O3)C4=CC=CC5=C4C=CC=C5
Molecular Formula
C24H23ClN2O3S
Molecular Weight
454.97
References & Citations
[1]Liu L, et al. Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1) . J Med Chem. 2022;65 (3) :2174-2190.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-142471A-01ZL-2201
HY-143902ZL-Pin01
HY-P991339ZL-1101
HY-158157ZL-28-6
HY-D2331-01ZL-12A probe
HY-142471ZL-2201 (free base)
HY-P76546-01PIN1, Human
HY-147710PIN1 inhibitor 2
HY-168038PIN1 ligand-1
HY-179577PIN1 degrader-3

Alternative Products

CatalogName
MBS5805489ZL-Pin13
MF-0100727-01ZL-1101
MBS5820308ZL-2201
MBS3600618-01ZL-006
MF-0138866-01ZL-Pin01
MF-0100732-01ZL-1102
MF-0117096-01ZL-12A probe
MF-0121570-01ZL-28-6
A24033-5BLU-945 (ZL-2313) 5mg
A24033-100BLU-945 (ZL-2313) 100mg

Popular Products