Thalidomide-O-PEG4-amine

CAT:

804-HY-141010

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CAS Number: 2401832-00-4
UNSPSC Description: Thalidomide-O-PEG4-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-o-peg4-amine.html
Solubility: 10 mM in DMSO
Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCCOCCOCCN)=O
Molecular Weight: 493.51
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-141010	Thalidomide-O-PEG4-amine
HY-141010A-02	Thalidomide-O-PEG4-amine (hydrochloride)
HY-141010B	Thalidomide-O-PEG4-amine (TFA)
HY-141010A-01	Thalidomide-O-PEG4-amine (hydrochloride)
HY-141010A-03	Thalidomide-O-PEG4-amine (hydrochloride)
HY-141014-03	Thalidomide-O-PEG4-Boc
HY-141014-01	Thalidomide-O-PEG4-Boc
HY-141014-02	Thalidomide-O-PEG4-Boc
HY-140844-02	Thalidomide-O-PEG4-azide
HY-140844-01	Thalidomide-O-PEG4-azide