Products for Research Use Only
RegisterLogin

Thalidomide-O-PEG4-Boc

CAT: 0804-HY-141014-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-141014-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Thalidomide-O-PEG4-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
CAS Number
2411681-87-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidomide-o-peg4-boc.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Molecular Formula
C28H38N2O11
Molecular Weight
578.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Related Products

CatalogName
HY-140844-01Thalidomide-O-PEG4-azide
HY-W800655-01Thalidomide-O-PEG4-acid
HY-141010Thalidomide-O-PEG4-amine
HY-131159-01Thalidomide-O-C8-Boc
HY-141010A-01Thalidomide-O-PEG4-amine (hydrochloride)
HY-141011-01Thalidomide-O-amido-PEG4-azide
HY-141012-01Thalidomide-O-PEG4-NHS ester
HY-141010BThalidomide-O-PEG4-amine (TFA)
HY-141013-01Thalidomide-O-amido-PEG4-propargyl
HY-161185Thalidomide-piperidine-O-azetidine-boc

Alternative Products

CatalogName
BA3259-250Thalidomide-O-PEG4-Boc
BA3145-50Thalidomide-O-PEG4-azide
T206263-01Thalidomide-O-PEG4-acid
MD329006-4Thalidomide-O-PEG4-N3
MD329007-4Thalidomide-O-PEG4-Propargyl
MD329025-4Thalidomide-O-PEG4-SPA
BIPC1005-01Thalidomide-O-PEG4-Amine
MD329005-4Thalidomide-O-PEG4-NH2
BA3042-100Thalidomide-O-amido-PEG4-azide
BIPC1009-01Thalidomide-O-PEG4-NHS ester

Popular Products