XR8-69

• UNSPSC Description:

  XR8-69 is a SARS-CoV-2 PLpro inhibitor that shows low micromolar antiviral potency in SARS-CoV-2-infected human cells.

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/xr8-69.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](C1=CC=CC(C2=CC=C(CNC(C)=O)S2)=C1)C)C3=CC(NC4CNC4)=CC=C3C

• Molecular Weight:

  462.61

• References & Citations:

  [1]Shen Z, et al. Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity. J Med Chem. 2021 Oct 19:acs.jmedchem.1c01307.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2817811-10-0