ASC-69

• Description :

  ASC-69 (APY69) is a potent and promising PD-1/PD-L1 small-molecule inhibitor[1].

• Product Name Alternative :

  APY69

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PD-1/PD-L1

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/asc-69.html

• Purity :

  99.63

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  N#CCC1=CC=C(NC2=NC(C)=CC(NC3=NNC(C4CC4)=C3)=N2)C=C1

• Molecular Formula :

  C19H19N7

• Molecular Weight :

  345.40

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Song Z, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021;64 (22) :16687-16702.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1216665-50-7]