ASC-69

• UNSPSC Description:

  ASC-69 (APY69)is a potent and promising PD-1/PD-L1 small-molecule inhibitor[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/asc-69.html

• Purity:

  99.63

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  N#CCC1=CC=C(NC2=NC(C)=CC(NC3=NNC(C4CC4)=C3)=N2)C=C1

• Molecular Weight:

  345.40

• References & Citations:

  [1]Song Z, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021;64(22):16687-16702.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1216665-50-7