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EGFR-IN-69

CAT: 0931-T73153-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73153-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2433837-65-9
Target
Others, EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Others
Bioactivity
EGFR-IN-69 is a potent inhibitor of the EGFR enzyme, demonstrating IC50 values of 4.3 nM for EGFR L858R/T790M/C797S, 6.6 nM for EGFR L858R/T790M, and 25.6 nM for EGFR 19del/T790M/C797S. This compound is utilized in the research of non-small-cell lung cancer (NSCLC) .
Smiles
ClC=1C(C=2C=3C(N(S(CC)(=O)=O)C2)=CC=CC3)=NC(NC4=C(OC)C=C(C(Cl)=C4)N5CCC(CC5)N6CCN(C)CC6)=NC1
Molecular Formula
C31H37Cl2N7O3S
Molecular Weight
658.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C