Products for Research Use Only
RegisterLogin

MLKL-IN-1

CAT: 0804-HY-139878Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-139878Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MLKL-IN-1 is a covalent MLKL inhibitor with a KD of 50 μM.
CAS Number
2837019-30-2
UNSPSC
12352005
Target
Mixed Lineage Kinase
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mlkl-in-1.html
Solubility
10 mM in DMSO
Smiles
OC(C1=CC=C(N=C([C@@H](OC)C2=CC=C(C(C)C)C=C2)N3)C3=C1)=O
Molecular Formula
C19H20N2O3
Molecular Weight
324.37
References & Citations
[1]Rübbelke M, et al. Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain. J Med Chem. 2021 Nov 11;64 (21) :15629-15638.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-141889-01MLKL-IN-2
HY-151542MLKL-IN-4
HY-156119-01MLKL-IN-6
HY-151541MLKL-IN-3
HY-161361MLKL-IN-7
HY-148767MLKL-IN-5
HY-P702574-01MLKL, Human (His)
HY-P80227-01MLKL Antibody (YA289, Rabbit)
HY-169072PROTAC MLKL Degrader-2
HY-P86228-01MLKL Antibody (YA5920, Rabbit)

Alternative Products

CatalogName
T60885-01MLKL-IN-1
MBS8563429-01MLKL
T79831-01PROTAC MLKL Degrader-1
GTR17695953Phospho-MLKL/MLKL Rabbit Monoclonal Antibody
BA6509-5.1MLKL-IN-2
T209391-01MLKL-IN-7
GWB-MS902BMLKL Antibody
AF6903-BPMLKL Peptide

Popular Products