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PROTAC MLKL Degrader-1

CAT: 0931-T79831-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79831-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
MLK, Others, PROTACs
Related Pathways
MAPK, PROTAC, Others
Bioactivity
PROTAC MLKL Degrader-1 (Compound 36) is a selective PROTAC degrader targeting MLKL, with a degradation maximum (D max) exceeding 90%. The compound incorporates modified cereblon (CRBN) ligands and a lenalidomide-linker within its structure, effectively inhibiting cell death in a TSZ-induced model of necroptosis.
Molecular Formula
C46H55F2N9O9S
Molecular Weight
948.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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