ABP 25

• Description :

  ABP 25 is an activity-based probe for cathepsin K imaging with excellent potency and selectivity.

• UNSPSC :

  12352005

• Target :

  Cathepsin

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/abp-25.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C(/C=C/C=C/C=C1N(C)C(C=CC=C2)=C2C\1(C)C)=[N+]3CCCCC(N[C@@H](CC(C)C)C(NC/C=C/C(N(CC4=CC=CC=C4)CC5=CC=CC=C5)=O)=O)=O)(C)C6=C3C=CC=C6.[Cl-]

• Molecular Formula :

  C55H66ClN5O3

• Molecular Weight :

  880.60

• References & Citations :

  [1]Lemke C, et al. An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity. J Med Chem. 2021 Sep 23;64 (18) :13793-13806.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Cathepsin K

• CAS Number :

  [2965359-45-7]