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ABP 25

CAT: 0804-HY-139685Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-139685Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABP 25 is an activity-based probe for cathepsin K imaging with excellent potency and selectivity.
CAS Number
[2965359-45-7]
UNSPSC
12352005
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/abp-25.html
Solubility
10 mM in DMSO
Smiles
CC(C(/C=C/C=C/C=C1N(C)C(C=CC=C2)=C2C\1(C)C)=[N+]3CCCCC(N[C@@H](CC(C)C)C(NC/C=C/C(N(CC4=CC=CC=C4)CC5=CC=CC=C5)=O)=O)=O)(C)C6=C3C=CC=C6.[Cl-]
Molecular Formula
C55H66ClN5O3
Molecular Weight
880.60
References & Citations
[1]Lemke C, et al. An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity. J Med Chem. 2021 Sep 23;64 (18) :13793-13806.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cathepsin K

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