Thalidomide-5,6-Cl

Thalidomide-5,6-Cl

• CAS Number: 2648939-40-4
• UNSPSC Description: Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.
• Target Antigen: Apoptosis; Autophagy; Ligands for E3 Ligase
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-5-6-cl.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NC(C(CC1)N2C(C3=CC(Cl)=C(C=C3C2=O)Cl)=O)=O
• Molecular Weight: 327.12
• References & Citations: [1]Zhang NN, et, al. A Thermostable mRNA Vaccine against COVID-19. Cell. 2020 Sep 3;182(5):1271-1283.e16.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported